What makes scars appear?
Psychosocial Sequelae of Scarring, Surgery for Scars, Scars Treatment Benefits, Individual Scars Formation Potential

Why do we Scar?

Summary: Scars can arise after almost every dermal injury. While for some people they are something unimportant, some others can suffer from severe scarring, deformations and even functional alterations.

Click: What makes scars appear? to read why this biological skin care solution is the most complete and balanced natural solution for all types of skin concerns.

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Scars are the end point of the normal continuum of mammalian wound repair. The ideal end point would be total regeneration, with the new tissues having the same structural, aesthetic, and functional characteristics as the original healthy skin. Scarless skin healing occurs in early mammalian embryos and complete regeneration occurs in smaller vertebrates, such as lizards, and some invertebrates (spineless creatures).

What, if any, are the advantages of scarring, and why do we scar?

A reasonable hypothesis is that wound healing is evolutionarily optimized for quick healing under septic conditions, where a multiple and redundant, compensating and quick inflammatory response with overlapping cytokine and inflammatory cascades allows the skin to heal quickly to prevent infections and future wound breakdown. A scar could be the price we pay for evolutionary survival after wounding.

Skin scarring: the clinical problem

Scars arise after almost every dermal damage-rare exceptions include tattoos, small scratches, and punctures of veins to take blood samples. Scars are often considered unimportant, but they can be disfiguring and aesthetically unpleasant and cause severe itching, tenderness, pain, sleep disturbance, anxiety, depression, and disruption of daily activities. Other psychosocial sequelae include development of posttraumatic stress signs, loss of self esteem, and stigmatization, resulting in diminished quality of life. Physical deformity as a result of skin scar contractures can be disabling. Many scars take two to three years to pale and mature.

In spite of media suggestions to the contrary, scars cannot yet be made to disappear. A lot of people arrive at plastic surgery clinics with unfounded expectations. Medical judgment is required when considering treatment, balancing the theoretical benefits of the different treatments available against the possibility of a poor improvement and possible infectious complications.

There is considerable quantitative and qualitative difference in scarring potential between individuals and even within the same individual. Scars are normally worst in the deltoid and sternal regions and best in intraoral tissues, showing biological and mechanical differences between those sites. Wounds in adolescents and young adults normally results in bigger scarring than does similar injury in elderly people, reflecting the altered inflammatory and cytokine profile of old wounds, which in many respects are similar to those of the early embryo. People with dark skin are more prone to severe skin scarring than white people.

For the treatment of newly formed stretch marks, to strengthen fragile skin, tighten and firm breasts and other areas, reduce cellulite and prevent stretch marks during pregnancy.

Made in the USA. One Month's supply 180 grams = 6 oz

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Ultra Exfoliate Your Skin with BIOSKINEXFOL

A home microdermabrasion cream with the same high quality micro-crystals professionals use to breakdown hard, rough and old scar tissues, and allow for a deeper penetration of our exclusive natural skin moisturizing and skin regeneration complex compound contained in the microdermabrasion cream. For old and rough scars and stretch marks and to get rid of mild actinic keratosis scales before they turn into pre-cancerous formations. Not for keloids.

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Scarring can bring several physical and psychological problems. There's a need for a good enough Scar Treatment to avoid these troubles.

Recent Research about What makes scars appear?

Cellular changes in keloidal tissues

Lu F, Gao J, Ogawa R, Hyakusoku H.
Department of Plastic and Reconstructive Surgery, Southern Medical University, Guangzhou, China.

BACKGROUND: Expression of connexins and other constituent proteins of gap junctions along with gap junctional intercellular communication are key factors in the processes of cellular development and differentiation. In addition, an increasing number of hereditary skin disorders appear to be linked to connexins. Therefore, in this report, the authors studied in vitro gap junctional intercellular communication function and connexin expression in fibroblasts derived from keloid and hypertrophic scar patients.

METHODS: Fibroblasts harvested from each of six keloid and hypertrophic scar patients were used for this study. Gap junctional intercellular communication function was investigated using the gap fluorescence recovery after photobleaching method, and expression of connexin proteins was studied using quantitative confocal microscopic analyses.

RESULTS: Compared with normal skin, a decreased level of gap junctional intercellular communication was seen in fibroblasts derived from hypertrophic scar tissue, whereas an extremely low gap junctional intercellular communication level was detected in fibroblasts derived from keloid tissue. We also detected little connexin 43 (Cx43) protein localized in fibroblasts derived from keloids. Moreover, Cx43 protein levels were much lower in fibroblasts derived from hypertrophic scars than in those derived from normal skin.

CONCLUSIONS: The authors' data suggest that the loss of gap junctional intercellular communication and connexin expression may affect intercellular recognition and thus break the proliferation and apoptosis balance in fibroblasts derived from keloid and hypertrophic scar tissue.